I find this at least a little frustrating. I haven't used Emacs, but when using other apps that use non-standard defaults (or just defaults that I am not used to), changing one shortcut leads to a cascade where I have to change many shortcuts. I now have to spend a somewhat significant amount of time configuring a new piece of software before I even know if I actually like it.

Shipping with some easily configurable presets to mimic other popular tools would probably help new users a lot.