In a lot of ways, though, the European subjugation of the Americas was the "tutorial mode" for European subjugation of Asia and Africa. Among other things, note that the business end of European colonization of subsaharan Africa and South and East Asia started ~a century after the colonization of the Americas (thanks to proximity, the Middle East and North Africa were much more tightly coupled to European history, and colonization played out differently there). The scramble for Africa and the opening of Japan didn't happen until the mid-late 19th century!