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A comment on Canada's 'gamble' on delaying, mixing and matching Covid-19 vaccines paid off. Parent comment

Re:Canada's 'gamble' on delaying, mixing and matching Covid-... by refurb on Sunday October 10, 2021 @03:03AM (#28816402)
It’s not the exact same spike protein.
[ Parent | on HN ]
Re:Canada's 'gamble' on delaying, mixing and matching Covid-... by Causality1 on Sunday October 10, 2021 @10:00AM (#28818475)
The differences are stabilizers intended to prevent conversion of the labile form of the S protein. If the vaccines didn't work together then one or both of them wouldn't work at all.
[ Parent | on HN ]
Re:Canada's 'gamble' on delaying, mixing and matching Covid-... by bserge on Sunday October 10, 2021 @05:53AM (#28817140)
Even better? Immune system learns of two (slightly) different ones, making immunity more robust.
[ Parent | on HN ]
Re:Canada's 'gamble' on delaying, mixing and matching Covid-... by refurb on Sunday October 10, 2021 @06:23AM (#28817264)
That’s the logic, and the argument why actual infection with Covid produces an even better immune response than mixed vaccines.

But that’s by no means a guaranteed outcome. Mixed vaccines could have resulted in mediocre immune response to two different spike protein profiles.

[ Parent | on HN ]