From what I understand doing donations and stipulating that it’s for a specific purpose can hurt a nonprofit more than help, because then vital logistics get underfunded and fuck up the competency of the organization. (Eg. Everyone wants to fund nonprofits cancer research or whatever, but what if they actually desperately need to fund remote work infrastructure because a global pandemic has forced them all to work remotely on short notice?)

Of course if you don’t like what an organization broadly does with the money given to it, don’t give it money. Maybe issue some feedback that you think the organization should do x or y, and the fact it’s doing p and q makes you hesitant to donate.