We had various project constraints and user demands that made most of those suggestions untenable. We used pagination in some places, but in others our users refused to accept it (they wanted Ctrl+F, fast browsing of huge datasets, etc). Writing a native app would have been miles outside the realm of possibility (we had a small team making a very complex product, none of us had native app experience, we needed to support multiple platforms, we specifically needed instances of our server to be able to serve up their own GUI, we needed to be able to interface with them from arbitrary remote machines without installing new software, etc).
To use the words of a commenter in another thread: I didn't provide sufficient information for informed responses. It was just a general comment about why I'm excited for React 18 to help better manage concurrency in a number of ways.
Maybe that's the real problem? If at all possible, such intensive tasks should be done in native frameworks, not web technologies. Alternatively, why not simply do less? Pagination, extracting separate sections of the app into separate pages/views and many others are perfectly valid approaches to something like that in my eyes, not just turning to low level optimizations.