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Re:Why You Should Not Use Ivermectin to Treat or Prevent Cov... by off_sounder on Monday September 13, 2021 @07:06PM (#28518068)
I'm skeptical about the efficacy of the SARS-CoV-2 vaccine over longer periods of time.

I've still not heard a reasonable explanation about why this vaccine is expected to work long-term when the flu shot clearly does not. Especially since SARS-CoV-2 mutates faster than the flu virus.

Can anyone give me an explanation of why vaccines are touted for fast-evolving viruses like the flu and SARS-CoV-2?

Re:Why You Should Not Use Ivermectin to Treat or Prevent Cov... by kazinator on Monday September 13, 2021 @07:26PM (#28518228)
There cannot be a the vaccine; obviously, SARS-CoV-2 vaccines will have to be updated. People will need boosters.

> I've still not heard a reasonable explanation about why this vaccine is expected to work long-term when the flu shot clearly does not

I don't think anyone in their right mind claims or believes such a thing, or believes that the health authorities are trying to convince them of such a thing. Depending on what we mean by "long term".

> SARS-CoV-2 mutates faster than the flu virus.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137987/

"Compared with other RNA viruses such as HIV and influenza virus, SARS-CoV-2 accumulates mutations much more slowly (15, 28)."

So that would by why you can expect more mileage from SARS-CoV-2 vaccines.

Re:Why You Should Not Use Ivermectin to Treat or Prevent Cov... by mikem170 on Monday September 13, 2021 @07:11PM (#28518118)
>Especially since SARS-CoV-2 mutates faster than the flu virus.

This doesn't jive with what I have heard, that SARS-CoV-2 mutates rather slowly, like other coronaviruses.

And that the flu is completely different, having the ability to recombine parts, which is why we have a different strain every years, aka H1N1, H2N1, H2N2, etc. Every year they have to guess which one will be prevalent, therefore the yearly flu shots.

SARS-CoV-2 has not mutated into a different strain (variants are not strains), and is not expected to. Immune system response for other coronaviruses has been observed to be long lasting (17 years for SARS-CoV-1).

Re:Why You Should Not Use Ivermectin to Treat or Prevent Cov... by grepfru_it on Monday September 13, 2021 @09:12PM (#28518987)
> Especially since SARS-CoV-2 mutates faster than the flu virus.

The SARS-cov-2 proofreading mechanism would like to have a word with your horribly inaccurate point