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Re:FDA Approves First Covid-19 Vaccine by miked85 on Monday August 23, 2021 @10:34AM (#28276377)
> I’m wondering what the odds are that people will pivot from “it’s experimental” to “it was rushed due to politics/greed”.

Or maybe just stick with the fact that it isn't very effective. [1]

[1] https://www.medrxiv.org/content/10.1101/2021.08.06.21261707v...

Re:FDA Approves First Covid-19 Vaccine by endisneigh on Monday August 23, 2021 @10:37AM (#28276417)
That’s not really what your link says tho.

> Both vaccines were highly effective during this study period against SARS-CoV-2 infection (mRNA-1273: 86%, 95%CI: 81-90.6%; BNT162b2: 76%, 95%CI: 69-81%) and COVID-19 associated hospitalization (mRNA-1273: 91.6%, 95% CI: 81-97%; BNT162b2: 85%, 95% CI: 73-93%). However, in July, the effectiveness against infection was considerably lower for mRNA-1273 (76%, 95% CI: 58-87%) with an even more pronounced reduction in effectiveness for BNT162b2 (42%, 95% CI: 13-62%). Notably, the Delta variant prevalence in Minnesota increased from 0.7% in May to over 70% in July whereas the Alpha variant prevalence decreased from 85% to 13% over the same time period.

Re:FDA Approves First Covid-19 Vaccine by miked85 on Monday August 23, 2021 @10:41AM (#28276488)
You literally posted the part describing how much effectiveness has dropped with variants.
Re:FDA Approves First Covid-19 Vaccine by endisneigh on Monday August 23, 2021 @10:45AM (#28276536)
Two doses of Moderna is still highly effective. What are you going to do? Stay unvaccinated?

Given that both Pfizer and Moderna have virtually no side effects why wouldn’t you get it at these efficacy rates, even if lower?

Re:FDA Approves First Covid-19 Vaccine by miked85 on Monday August 23, 2021 @10:52AM (#28276672)
I've got the vaccine, I am not saying don't get it. I am saying those who choose not to get it have very valid reasons for it.
Re:FDA Approves First Covid-19 Vaccine by endisneigh on Monday August 23, 2021 @10:53AM (#28276692)
Not really. Basically you get 45-75% efficacy or you roll the dice on getting Covid and potentially dying depending on age.

Not to mention your article was about infection not hospitalization. If you do that it makes even less sense.

Re:FDA Approves First Covid-19 Vaccine by hajile on Monday August 23, 2021 @12:36PM (#28278452)
The real question is about future strains. COVID was pretty much completely stable for over a year (minor variants without anything super significant changing). Once the vaccine was introduced, a bunch of variants started popping up.

It makes perfect evolutionary sense. Loads of variations appear in every infected individual. The most effective version takes over and is most likely to be passed on to others.

Most vaccines are so effective that the virus never gains a foothold. With the mRNA vaccines, people still get sick. You get tons of mutations and the original strain is no longer the most efficient because of the vaccine. so now there's tons of room for variants to form which work around the vaccine. Once an effective bypass happens, it takes off and you instantly get a new strain, but more resistant.

At the current rate, we're only a few short jumps away from a completely ineffective vaccine.

Re:FDA Approves First Covid-19 Vaccine by lots2learn on Monday August 23, 2021 @12:51PM (#28278690)
There were already 7 known variations when the vaccines were introduced. Furthermore, none of the vaccines currently approved for use (at least in the US) have the live virus. So vaccines are not "causing mutations". Mutations happen during replication within infected cells. The vaccines will greatly reduce the number of cells that will get infected. So vaccines reduce mutations and chances of strains to take hold. Unvaccinated people who become infected are what will fuel strains.
Re:FDA Approves First Covid-19 Vaccine by Saint_Genet on Monday August 23, 2021 @11:54AM (#28277790)
1. That article isn't peer reviewd.

2. You linked to an old version that says "However, in July, the effectiveness against infection was considerably lower", in the current version the same sentence reads "In July, vaccine effectiveness against hospitalization has remained high"

Re:FDA Approves First Covid-19 Vaccine by hypocritepledge on Monday August 23, 2021 @12:03PM (#28277945)
You say it "isn't peer reviewed". I say it's a "preprint paper".

That's generally how the media describes the papers that respectively go against, or with the narrative they're trying to push.

Re:FDA Approves First Covid-19 Vaccine by nojito on Monday August 23, 2021 @10:37AM (#28276424)
Did they ever make their data available?