> Both vaccines were highly effective during this study period against SARS-CoV-2 infection (mRNA-1273: 86%, 95%CI: 81-90.6%; BNT162b2: 76%, 95%CI: 69-81%) and COVID-19 associated hospitalization (mRNA-1273: 91.6%, 95% CI: 81-97%; BNT162b2: 85%, 95% CI: 73-93%). However, in July, the effectiveness against infection was considerably lower for mRNA-1273 (76%, 95% CI: 58-87%) with an even more pronounced reduction in effectiveness for BNT162b2 (42%, 95% CI: 13-62%). Notably, the Delta variant prevalence in Minnesota increased from 0.7% in May to over 70% in July whereas the Alpha variant prevalence decreased from 85% to 13% over the same time period.
Given that both Pfizer and Moderna have virtually no side effects why wouldn’t you get it at these efficacy rates, even if lower?
Not to mention your article was about infection not hospitalization. If you do that it makes even less sense.
It makes perfect evolutionary sense. Loads of variations appear in every infected individual. The most effective version takes over and is most likely to be passed on to others.
Most vaccines are so effective that the virus never gains a foothold. With the mRNA vaccines, people still get sick. You get tons of mutations and the original strain is no longer the most efficient because of the vaccine. so now there's tons of room for variants to form which work around the vaccine. Once an effective bypass happens, it takes off and you instantly get a new strain, but more resistant.
At the current rate, we're only a few short jumps away from a completely ineffective vaccine.
2. You linked to an old version that says "However, in July, the effectiveness against infection was considerably lower", in the current version the same sentence reads "In July, vaccine effectiveness against hospitalization has remained high"
That's generally how the media describes the papers that respectively go against, or with the narrative they're trying to push.
Or maybe just stick with the fact that it isn't very effective. [1]
[1] https://www.medrxiv.org/content/10.1101/2021.08.06.21261707v...