Historically, biological warfare research has focused on pathogens like anthrax that have very low human-to-human transmission risk, for two reasons. One is that, if your germ-warfare bomb starts an epidemic, it barely matters which sides of the battle lines it falls on; if it thins your own ranks less than those of the enemy, it's only because your troops (and their families dying back home) are in better condition or have better sanitary measures in place. The other is that, if you can't stop the deaths when the enemy surrenders, the germ-warfare bomb doesn't give the enemy any incentive to surrender.
Evil things do happen fairly regularly on a grand scale. But doing things on a grand scale has historically required a centralized government to organize them. That's still true for a little while longer.
Anywho, I've long since realized that it's all too-easy to do both sabotage, terrorism and other evil things very easily without being caught. The fact that it doesn't happen fairly regularly on a grand scale that brings society to a halt though makes we wonder if there are an appreciable amount of such evil people that are willing or incentivized to do those evil acts. A sort of "Drake equation" look at it, I guess.