Edit - The Ford F-150 is the best selling "car" in the US by a long shot. That isn't all fleet sales - a significant number of normal people own trucks for one reason or another (myself included - Honda Ridgeline).
You need a heck of a lot of 10-15mpg vehicles to drag the fleet average down to 22. Most white collar employees who own trucks aren't commuting in them and even then there's more people commuting in 40+mpg subcompacts and hybrids so it should more than balance out.
Look at a high class parking garage, 22mpg just doesn't pencil out. 28-30mpg sounds believable.
Welcome to Texas.
> Fuel cost estimates assume national average fuel prices and assume you drive 15,000 miles each year, 45% under highway driving conditions (steady speeds with little or no stopping) and 55% in city driving (low speeds with lots of stopping).
Noting that I'm not the typical home worker, but I went from an average of 600 miles/month (7200 miles/year) to 30 miles/month over the past year and a half. This took my carbon footprint for driving from 1.7 T/y to 0.1 T/y.
The flip side of this number is (for me) that I went from heating the house only a few hours a day in the winter to heating or cooling one room to comfortable. I don't have good numbers on my electrical footprint change. This would again be different with different life circumstances (number of other people in the house, size of house / apartment, etc...)
I'd pad the estimate for carbon saved and say like 3.5ton/yr per work from home employee.