Not in terms of long term data, at all
These are serious long-term concerns, which may not manifest overnight, but they are certainly on the radar of many experts in the field.
[1] Risk of rapid evolutionary escape from biomedical interventions targeting SARS-CoV-2 spike protein https://pubmed.ncbi.nlm.nih.gov/33909660/
[2] SARS-CoV-2 immune evasion by the B.1.427/B.1.429 variant of concern https://science.sciencemag.org/content/early/2021/06/30/scie...
[3] Imperfect Vaccination Can Enhance the Transmission of Highly Virulent Pathogens https://journals.plos.org/plosbiology/article?id=10.1371%2Fj...
Also, anything being possible is not the same as anything being probable. The vaccine might make me grow a third arm too, after all anything is possible in the long run, but you would laugh if I said that I wasn’t getting a vaccine for the fear of my tailoring bill.
> A vaccine that provides for only a year is hardly the same as a booster shot which is good for 10 iirc.
As compared to the flu shot? The one that I’ve been given for free in every school and workplace I’ve attended in the past twenty years?
Logistically, yearly shots are nbd. Maybe we should make flu shots mandatory for education just like the MMR shot, given the number of kids killed by the flu every year.