My housemate is an organic chemist and from a past conversation apparently there is a cautionary paper regarding a grad student who lost a hand due to delayed amputation of a finger after similarly being jabbed with some nasty chemical. Can’t find the paper unfortunately.

At the very least a tourniquet could be considered. It only takes one protein to get through though.

>would the blood pump so fast that the prion(s) is already in your body.

Well, I guess the question is "is it in the blood yet or not". As someone who have had lots of stuff injected into his veins multiple times (cancer treatment) I can state for a fact the from injection until pretty much full body exposure can be counted in seconds on one hand. I'm not a doctor but my guess is it would only work if you cut the finger off pretty much instantly (counting from the time it enters the bloodstream). Of course it would take longer from a small cut than injected into the big pipes. I wouldn't trust it to work after a few seconds though.

They mention in the article that normal protocol is to immediately soak the thumb in bleach. Not sure if that’s actually effective though, or just hopeful.

Wow be glad Trump didn't suggest that.

Just don't use the same saw.