A practical application of this is to suggest that those who want to use cannabis for a good night;s sleep, get started two or three hours before bedtime.
I got twenty excellent years out of regular cannabis use. Tradeoffs there were, but worth it.
I'm a lot more sensitive now and sometimes it gives me panic attacks. But even when it doesn't, cannabis consistently raises heart rate and lowers blood pressure, that's just how it works.
I still employ it, carefully, from time to time.
Have you tried using the minimal amount of very low-potency weed?
In my experience negative effects like paranoia and panic attacks come from overdose, either by using high-potency weed and/or smoking too much.
Panic attacks are well under a 1 in 20 response now or I just wouldn't bother, since it isn't any fun at all for about 20 (subjectively very long) minutes.
I generally suffer exclusively the singular negative effect of others finger wagging and disapproval of a rather pleasurable funcional vice or medication or whatever you wish to call it.
I’ve quit a few times for up to a year and always decided consciously to go back. One of the times I left tobacco behind. Countless studies will only ever have access to what users are willing to divulge, to the degree that it’s not an open regulated or at least informed market.
There is an interesting singular fact. Not one single overdose death has ever been conclusively linked to cannabis. The LD50 is something crazy like 15kg in the span of 15 minutes for a 75kg human.