With hundreds of millions of people having received mRNA vaccines by now, we most likely have seen all the short term side effects that there are, except the rarest of them. I would not worry too much about these either.
> Overall, the robust inflammatory milieu induced by LNPs, combined with presentation of the vaccine-derived peptides/protein outside of antigen-presenting cells, might cause tissue damage and exacerbate side effects. Since self-antigen presentation in an inflammatory environment has been linked to autoimmune disease development (Charles A Janeway et al., 2001), this merits further investigation, albeit not detected here.
Because short term inflammation is, as far as I know, not a big deal and somewhat desirable for vaccinations? It is my understanding that we intentionally mix in inflammatory substances ("adjuvants") with normal vaccines to kick the immune system into action?
Lead poisoning for example takes years to manifest itself.
So did other drugs which took years until regulators retracted them because they did more harm then good.
Specifically about mRNA vaccines, we know little about the long term effects of the lipid nano particles used in them and there are reasons to be concerned.