There are some more problematic areas where the Constitution itself is inconsistent. Copyright should not exist, for one; the core concept is utterly incompatible with freedom of speech. The Supreme Court even recognized this at one point—it's why we have the concept of "fair use" in the first place—but "fair use" is a poor compromise which does not fully negate the infringement of the freedom of speech. When you have one clause saying that Congress has the power (but not the obligation) to do something which would infringe on the freedom of speech, and another clause later passed as an amendment saying "Congress shall make no law... abridging the freedom of speech", the obvious reconciliation of these clauses is that Congress is barred from exercising that enumerated power because it would violate the later amendment. The Court tried to strike a balance instead… but it still amounts of Congress passing a law which abridges the freedom of speech, despite the limitations imposed by the Court.
I should note that I am anti-censorship and consider such laws absurd, but my point is that we can't rely on readings of the constitution to self-evidently protect us from such things.
What part of "shall make no law" isn't clear? It's true that obscenity is an exception to 1A, but that's something that some people made up after the fact, in direct contravention to the framers' stated intention.
The founders weren't short on ink. If they had wanted to equivocate, they were certainly free to do so. The fun really starts when some people decide that their (least) favorite amendments are subject to less (more) interpretation than others.