I stopped using classic ads for monetarization years ago. Coming from someone who lived of AdSense for a while.

What I do is Building relevant ads to my content when I find fitting affiliate programs. As they are just text (or image) with an link they ain't blocked and respect my users privacy.

I would argue that are the only actually targeted ads. And lucky content creators won't be blocked either (usually)

Other projects I just go for a paid or free/paid model.