Some people also reply with a sterner 'no, don't reply again'. To them, I do not even reply with a 'Thanks, no problem' message since I'm scared they will mark me as spam!
We live in high turnover of information, and if I received your first email (which I did) and didn't respond, it does mean I am not interested. Sending a follow up would just spark frustration.
Again, perhaps it's just me and this approach works for most people, but it may be useful to know it does not for all.
From his perspective though, he doesn't lose anything by sending the follow up, and if it is the second case, may gain a sale.
Of course it doesn't work for non organised individuals and people who succumb under pressure.
It goes without saying that some of my outreaches get thrown there too by default.
So, as the sender, I don't really know if you saw the message and didn't want it, or if you were too busy to reply, or that you did not receive my message in the first place.
There are, of course, many email tracking tools available. I do not use them though.
In each of my follow-ups, I mention that I am reaching them because I did not hear from them the previous time, and ask them to reply one way or the other.
It communicates to them that if they just reply a 'No', I would stop,
Also, I do not persist forever. My follow ups are always 4 levels deep, and in the final mail, I make sure I tell that it's the last one and I won't send another one.
So anyone like OP who's delaying it simply because they are busy tend to reply.
Again, I am not sure if these are ideal tactics, but they seem to work for me.