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Re:Brain imaging before and after Covid-19 in UK Biobank by captainredbeard on Sunday June 20, 2021 @10:58AM (#27570655)
It’s more the effects of free circulating spike protein in the bloodstream than mRNA triggering ribosomes.
Re:Brain imaging before and after Covid-19 in UK Biobank by Majromax on Sunday June 20, 2021 @11:58AM (#27571310)
> It’s more the effects of free circulating spike protein in the bloodstream than mRNA triggering ribosomes.

The mRNA vaccines are designed to express the spike protein in a membrane-bound form; very little is found floating free. See https://www.deplatformdisease.com/blog/spike-protein-circula....

Additionally, the mRNA vaccines express a modified spike protein that is stabilized in its "prefusion" state (as seen on the virus itself before it binds with a cell), and the resulting complex seems to have somewhat fewer effects even when it does interact with a cell.

Re:Brain imaging before and after Covid-19 in UK Biobank by lima on Sunday June 20, 2021 @11:15AM (#27570819)
And cytotoxicity - with the second shot, the body will have cytotoxic T cells which could target some of the transfected cells.

But, why not to be worried:

- It's a normal process and most cells will be replaced.

- The effects would be tiny, especially compared to an infection with the real thing. If this was causing widespread issues, we would know by now.

- All studies done so far indicate that only a very small amount will enter systemic circulation.

It's a classic risk tradeoff, and the risks of taking the vaccine are much smaller than the risk of getting the real infection (billions of viruses replicating vs. one-time dose, real spike protein vs. stabilized spike protein).

Re:Brain imaging before and after Covid-19 in UK Biobank by ganzuul on Sunday June 20, 2021 @11:10AM (#27570774)
I don't understand what you are saying.

What is the significance of either of those?