Re:The mechanisms of action of Ivermectin against SARS-CoV-2
by Khelavaster on Tuesday June 15, 2021 @12:56PM
(#27518149)
Ivermectin is absolutely an antiviral drug. It blocks cells' α/β nuclear import protein--also used by a great number of RNA-based viruses--while letting other nuclear import proteins function normally.
"The well-tolerated drug ivermectin may hold great potential for treatment of YFV [yellow fever virus] infections. Furthermore, structure-based optimization may result in analogues exerting potent activity against flaviviruses other than YFV." (2012)
"The well-tolerated drug ivermectin may hold great potential for treatment of YFV [yellow fever virus] infections. Furthermore, structure-based optimization may result in analogues exerting potent activity against flaviviruses other than YFV." (2012)
https://pubmed.ncbi.nlm.nih.gov/22535622/