What use is it other than novelty?
I mean if you live in Venice maybe?!
Or Vancouver, Seattle, San Francisco, New York, London ... basically any city with a harbor and big bridges crossing it. The ability to bypass the line for the bridge and drive a relatively strait line across the harbor to your destination is very appealing. The concept of hundreds, thousands, of tiny commuter boats crisscrossing a busy harbor is not. TopGear staged a race across London, with Clarkson driving by boat. It looks like lots of fun, so long as you are the one rich guy with the fastest boat on the river.
The situations where the bridge is very slow but past the bridge is not are probably sufficiently rare that it is not worth the extra complexity of an amphibious car for most people.
It might be more interesting and attractive in places without bridges. Depending on the speed and frequency of a ferry service, it is possible that the car on water would be faster.
Ferries will usually travel faster (the Seattle car ferries are around 2.5 times as fast as the Amphicar, and the fast passenger ferries are about 5 times as fast), but the Amphicar could still win if you have to wait a long time between ferries.
For example, the car would take about 2 hours to go from Seattle to Bremerton via the water. The state ferry on the same route would take about an hour, but the ferries are almost 2.5 hours apart so it would take you from 1 hour to 3.5 hours by ferry depending on how your trip aligns with the ferry schedule. (The car could do it in 90 minutes if you went by land instead, but that route goes through Seattle and Tacoma, so you could hit a lot of traffic which could slow you down considerably).
Why is that? Is it that people aren't interested? I would love to own an amphibious car!! Or is it that it's not feasible to make one for a reasonable price? Will the electric engine change anything, maybe?