We absolutely have enough data to rule out meaningful ADE. Study after study (the phase 3 trials and all the ongoing surveillance) indicates a massive reduction in the rate of severe infection among vaccine recipients.

Sure, one can quibble about whether maybe some of the very small number of people who got a vaccine more than a couple weeks before a severe COVID case had a form of ADE, but that’s like saying that we haven’t ruled out that seatbelts might kill people. In both cases, the risk that a protective measure harms the recipient is massively outweighed by the degree to which the protective measure protects the recipient.