I think the problem ailing cities is density. East Bay real estate booming while SF prices declining is possibly effect and cause. A tiny apartment in a dense city is not a great place to be in during a quarantine. And correct, the end to all of those commercial real estate leases means much less money going into the economy. New York and other big cities are facing the same doom-and-gloom narrative:

https://www.nytimes.com/2021/05/12/opinion/New-York-San-Fran...

So yes, SF's crime issues are a pervasive problem. But the current decline ultimately all come down to economic factors and simple geography. Maybe Boudin has exacerbated things, but he has been in office for a minute compared to the past decade of spiraling property crime in the city.