Mentally, probably. I think would have trouble speaking coherently long before the visuals became a problem, but then again everyone is different. It's not my experience that visuals get much more intense with anxiety.

With how long trips and the comeup take, I just have trouble understanding what kind of confidence it must take to walk in the meeting anyways and try to wing it. I would have found any excuse to sober up and get things in order before drunkely stumbling through a big pitch.