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A comment on What can mRNA treat next?. Parent comment

Re:What can mRNA treat next? by CorrectHorseBat on Sunday May 02, 2021 @11:23AM (#27016038)
I thought they solved that by replacing U by 1-methyl-3'-pseudouridylyl in mRNA vaccines? I can imagine it's not great for vaccines either, you want the immune system attack the spike the mRNA codes for, not destroy the mRNA before it can do it's thing.

https://berthub.eu/articles/posts/reverse-engineering-source...

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Re:What can mRNA treat next? by pfdietz on Sunday May 02, 2021 @05:01PM (#27018972)
You also don't want to activate an innate response our bodies have when virus attack is detected: cells churn out enzymes that chop up RNA.
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