The most effective malaria vaccine yet discovered

Re:The most effective malaria vaccine yet discovered by pjscott on Friday April 23, 2021 @06:26PM (#26919936)

It's bizarrely hard to find good explanations of this! The National Malaria Eradication Program, between 1947 and 1951, cut down on malaria transmission enough that the parasite was driven locally extinct. They drained wetlands where mosquitoes bred, sprayed house interiors and mosquito-heavy areas with DDT on a very large scale, and generally engineered a very specific ecological disaster, depriving the parasite of the human hosts needed for part of their reproductive lifecycle. Without enough infected humans, the parasites died out.

Crucially, they didn't need to get rid of all the mosquitoes to do this: they just needed to drive mosquito-to-human transmission low enough for long enough.

https://en.wikipedia.org/wiki/National_Malaria_Eradication_P...

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Re:The most effective malaria vaccine yet discovered by londons_explore on Friday April 23, 2021 @06:41PM (#26920080)

If this were the complete story then just a single person coming back to the USA infected would lead to mass infection...

Clearly that hasn't happened.

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Re:The most effective malaria vaccine yet discovered by Brybry on Friday April 23, 2021 @07:47PM (#26920624)

We do still have mosquito abatement programs too.

I know here in Louisiana the local abatement program has trucks that spray synthetic pyrethroid chemicals (resmethrin, sumithrin and prallethrin) at night and uses an organophosphate (naled) from planes.

And residents are routinely urged to be aware of and eliminate standing water on their property.

We just don't use DDT anymore -- we almost wiped out our state bird with it.

Edit: I have to wonder how much housing changes also mattered. With modern air conditioning and well sealed homes it's fairly rare to have mosquitoes in the home at night.

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Re:The most effective malaria vaccine yet discovered by Clewza313 on Friday April 23, 2021 @07:21PM (#26920422)

Malaria does not spread from human to human, you need infected mosquitos in the mix. So you would need to get a breeding population of infected mosquitos biting humans for it to start spreading.

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Re:The most effective malaria vaccine yet discovered by juskrey on Saturday April 24, 2021 @01:53AM (#26922590)

The answer is malaria eradication efforts never stopped neither in US nor in Europe. It's just as routine as renewing asphalt roads or maintaining sewers

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Re:The most effective malaria vaccine yet discovered by im3w1l on Friday April 23, 2021 @07:38PM (#26920554)

Only explanation I can think of is that the malaria from elsewhere is different somehow, worse adapted to US conditions.

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