News for hackers. Stuff that matters.

A comment on mRNA vaccines – a new era in vaccinology (2018). Parent comment

Re:mRNA vaccines – a new era in vaccinology (2018) by hartator on Wednesday April 21, 2021 @12:02AM (#26885298)
Moderna and Pfizer mRNA half life is actually 10 and 14 days. The human one is indeed hours. Which is fine but it’s indeed not clear in their communication.
[ Parent | on HN ]
Re:mRNA vaccines – a new era in vaccinology (2018) by franklyt on Wednesday April 21, 2021 @03:23AM (#26886391)
That’s a huge difference. Do you have a citation for this claim? I don’t doubt you, but, wow.
[ Parent | on HN ]
Re:mRNA vaccines – a new era in vaccinology (2018) by inglor_cz on Wednesday April 21, 2021 @08:08AM (#26888515)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076378/

Look at the section 4.1. Molecular Stabilization. Yes, it is a challenge, but a challenge that has been overcome.

[ Parent | on HN ]
Re:mRNA vaccines – a new era in vaccinology (2018) by hoseja on Wednesday April 21, 2021 @05:35AM (#26887281)
You can probably design the fragment so it doesn't mesh well with the recycling apparatus of the human cell but still works for transcription.
[ Parent | on HN ]