The responses here are surprising. Your trading activity should be based on a strategy with a clear point when you should exit, e.g. you should have a prediction of how high an asset will go and sell when it reaches that point, or some timeline/portfolio risk mix that determines when you sell. And adjust that strategy based on new information (e.g. if you have a credible reason for why that strategy is no longer applicable you should adjust). Everything else is subject to bias and emotion, which is only useful at the casinos.

That is, you should NOT sell something because you're becoming emotional drained by it as someone else suggested. That implies you're not fit for managing and investing your own wealth. Don't jump off a rollercoaster while you're still riding it.

If you don't know what your strategy would be for bitcoin or some other asset, you should figure that out before trading.