>Typing it out is O(1), having N people look it up is O(N) if you allow me to abuse the notation like that ;)

Thank you; this is a perfect way to put it. I always include links, and ideally inline text, when posting because I always try to think from the perspective of a lazy and/or context-switch-averse reader reading the comment. (Easy to do, since that's my actual perspective 99.9% of the time.) One of my highest-upvoted HN comments was just pasting the contents of a tweet someone else posted to save people a click. (https://news.ycombinator.com/item?id=25260896)

ISRIB works just as well as "integrated stress response inhibitor." There are multiple stress response inhibitors in the body, so it's not like the name tells you anything. Both are just arbitrary names.