The SD cards are nice for most use cases, but on some boards I'd really like to see a SATA port or M.2 slot which can be booted from and a x4 PCIe port (even if through an optional board or a HAT).
I see the SD cards on the Raspis as modern floppy discs. They are good to have, but not ideal for some cases.
People have already achieved it by hardware hacking
My hope is the next Pi model B might include an M.2 slot (maybe 42mm long) on the bottom.
Which ones are you seeing with M.2 slots? I've clicked a good 5-8 of the top listings from that list for which it would make sense to have such slot and they're missing it.
But that being said, I've burned out plenty an SD card. Haven't managed to do that to an eMMC module yet.
Also, on devices like the Beaglebone, you can use eMMC and an SD card at the same time.
Oh dear. That will involve the process of flashing OS onto the Pi and will increase the risk of bricking it. That is the reason for using SD cards instead of a NAND chip.
Secondly, you can't upgrade the storage on it either and would have to choose a RPi with fixed storage space on it. Might as well get a M1 Mac Mini.
I cannot imagine having to choose a future RPi 5 having either a 8GB, 16GB, 32GB NAND' and being unable to upgrade the space on it. So no thanks and no deal to (2).