Re:Moderna mRNA sequence released to GitHub [pdf]
by jonplackett on Monday March 29, 2021 @08:18PM
(#26629955)
Rather disappointingly, neither sequence includes the string 'GATTACA'
[ Parent
| on HN ]
Re:Moderna mRNA sequence released to GitHub [pdf]
by ImaCake on Tuesday March 30, 2021 @03:16AM
(#26631954)
A given combination of 7 bases has a probability of occurring of 1/16,384. Since the COVID genome is about 22k bases long I guess you have pretty good chance of it appearing in there somewhere. This assumes uniformity, which of course is not true. COVID’s genome is under crazy intense selection pressure!
Re:Moderna mRNA sequence released to GitHub [pdf]
by shellfishgene on Tuesday March 30, 2021 @05:16AM
(#26632548)
The sequence GATTCA appears 4 times in the reference version of the COVID genome :)
(Go to https://www.ncbi.nlm.nih.gov/nuccore/NC_045512, pick "Find in this Sequence" on the right)
Re:Moderna mRNA sequence released to GitHub [pdf]
by jonplackett on Tuesday March 30, 2021 @06:01AM
(#26632823)
AWESOME! I just did a text search for it on github. Maybe it didn't pick any up that had a line break in the middle.
I'm much happier now.
Re:Moderna mRNA sequence released to GitHub [pdf]
by ImaCake on Wednesday March 31, 2021 @05:38PM
(#26653479)
Yep, the usual coding tools aren't ideal for bioinformatics. We have our own set of tools that work well with the various "standard" formats for sequence data.
Re:Moderna mRNA sequence released to GitHub [pdf]
by calebm on Tuesday March 30, 2021 @12:38PM
(#26636829)
That would have been a killer easter egg (possibly literally).
Re:Moderna mRNA sequence released to GitHub [pdf]
by joe45643234 on Tuesday March 30, 2021 @09:01AM
(#26634068)
Whats special about this string?
Re:Moderna mRNA sequence released to GitHub [pdf]
by Duber on Tuesday March 30, 2021 @10:07AM
(#26634746)
It´s the title of a cult film: https://www.imdb.com/title/tt0119177/
Re:Moderna mRNA sequence released to GitHub [pdf]
by jonplackett on Thursday April 01, 2021 @07:21AM
(#26659013)
Very clever title. It was only much later I understood what it meant.