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Re:AstraZeneca may have provided incomplete efficacy data NIAID by addicted on Tuesday March 23, 2021 @08:22AM (#26554182)
AstraZeneca has no experience developing vaccines. As a result they’ve massively screwed up multiple times before. Frankly, even the original approval they got from the UK should never have been given, considering how tainted their original trials in Brazil were.

Basically what seems to have happened is that Oxford university developed the vaccine, required that companies who wanted to manufacture and sell it should not make a profit, and therefore only got companies with little vaccine development experience, such as AstraZeneca, which probably due to their lack of experience has been making mistake after mistake.

That being said, we have seen that with COVID the vast majority of vaccines have been extremely successful (some like the Russian and Chinese ones were deployed without complete testing and were shown to have great results), and since we are confident the AZ vaccine is safe enough, ans we can see the impact in the UK, there’s a strong justification to authorize using it even without proper results.

Just not in the US, which already has access to enough vaccines for its population without needing the AZ zone.

Re:AstraZeneca may have provided incomplete efficacy data NIAID by JamisonM on Tuesday March 23, 2021 @08:59AM (#26554448)
This comment is a valuable contribution to the discussion wrt AZ's lack of experience & screw ups.

Although I disagree that there was any reason to hold up UK approval, there was clear safety and effectiveness evidence that overwhelmed any doubts about safety in spite of the screw ups.

But I have zero sympathy for AZ even if many, many people are compounding their errors.

Re:AstraZeneca may have provided incomplete efficacy data NIAID by yread on Tuesday March 23, 2021 @02:45PM (#26558661)
Agree. Even the vaccine could have been done better - the spike protein RNA in the vaccine doesn't use the prefusion stabilization trick like the others.
Re:AstraZeneca may have provided incomplete efficacy data NIAID by linuxftw on Tuesday March 23, 2021 @09:30AM (#26554721)
Seems like anything made by this company should contain warnings like

"This manufacturer has never released an approved vaccine"

and

"This manufacturer is not allowed to make a profit on this product, so there is no monetary incentive to ensure quality after the product is authorized for emergency use"

I fully expect the same quality as soviet era cars.

Re:AstraZeneca may have provided incomplete efficacy data NIAID by michaelmrose on Friday April 02, 2021 @09:19PM (#26677623)
Why don't we look at the actual data instead of supposing? Presumably because it wouldn't support your conclusion in the slightest. Please don't promote anti vaxxer misinformation.
Re:AstraZeneca may have provided incomplete efficacy data NIAID by JamisonM on Tuesday March 23, 2021 @09:21PM (#26562440)
AstraZeneca has staked their reputation as an extremely large firm that makes all sorts of pharmaceuticals on the safety and efficacy of this vaccine, the idea that they have no incentive to ensure the quality of the product is absolutely bonkers.

Hilariously Lada cars - the Soviet era cars being referenced I expect - were exported for the express purpose of making a profit!

Re:AstraZeneca may have provided incomplete efficacy data NIAID by linuxftw on Wednesday March 24, 2021 @10:19AM (#26567552)
They can fall back on the usual refrain. "We didn't know" "We couldn't have known" "We used the best data available at the time" and they also have a new out "Blame Oxford, it was their drug" etc.

What's Pfizer's reputation? Seems to be fine among the masses, despite decades of mismanagement and killing people.