GNU Artanis, forget Hurd, get Guix. Also, on HTML/CSS/JS, they are still 20 years behind the Pascal IDE from Borland or Lazarus, and don't let me talk on NPM and dependencies.
On speed and features, QT5 slaps JS so hard that trying to get something as performant it's a ridiculous claiming.
And I use OpenBSD and CWM, but FFS, JS is a toy compared, to, for example, Lazarus IDE, QTCreator and their compilers/backends running fast as fuck software even on scrap computers.
And Turbo Pascal/Lazarus had RAD developing features since 20 years aso as I said. Something much faster and more native (totally native :p) than any JS toolkit is trying to do ever. Add a control? Drag and drop, edit the bindings. Cross compiling? Lazarus does that even for damn Windows 95 from a Linux machine. And so on.
Even then, there is no other ecosystem that has quite the volume of powerful tools and approaches that HTML/CSS/JS have.