I am cautious about these sorts of issues and typically buy the least processed oils (and foods in general) that I can find, however it is my understanding that humans around the world have been producing and eating (mechanically expressed) sesame seed oil for thousands of years. I can't say whether that has any impact on whether people are "evolved to eat it", but it's certainly not something new: https://link.springer.com/article/10.1007%2FBF02859136
The use of solvents to extract oils isn't a chemical reaction. It's not really different from using CO2 to extract caffeine from coffee, using water to extract tea from tea leaves, or using alcohol to extract vanilla flavor from vanilla beans. The common solvent for oil extraction is hexane, which is removed by boiling it off with a vacuum and/or heat.
The solvent-extracted oil will have unmodified molecules. The proportions of the various molecules may differ because the ease with which they are extracted will depend on the processing conditions. You get different proportions of molecules in the mix if you change the temperature, pressure, time, or solvent. For some use cases you might prefer one mix or another. You could get a different viscosity, melting point, or smoke point.
Now I see why they’re advertising the method of extraction...
Yes one can quibble that cooking is a chemical reaction, but it’s one that is both simple and that we’re long since evolved to tolerate.
I stick to mechanically produced vegetable oils and animal fats. It’s not only healthier but it tastes better too.
However, a healthy diet depends a great deal on your race. A traditional Inuit diet is observably healthy for Inuit persons, but probably best avoided by people like me. However there are no humans that are evolved to eat seed oils.