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Re:Sputnik V vaccine peer reviewed with efficacy of 91.6% by julienchastang on Wednesday February 03, 2021 @12:04AM (#26010771)
I share your skepticism. That said, Russia and the Soviet Union before have a long history in virus and phage research. They've been leaders in phage therapy [1], for example. Their expertise in this area may not be so far-fetched. Also [2].

[1] https://en.wikipedia.org/wiki/Phage_therapy

[2] https://www.nytimes.com/2020/06/24/world/europe/vaccine-repu...

Re:Sputnik V vaccine peer reviewed with efficacy of 91.6% by wahern on Wednesday February 03, 2021 @01:12AM (#26011079)
I don't think the Sputnik V vaccine has any substantive relationship to phage research and therapy. And I don't think there's much reason to doubt that Russian researchers could develop a solid vaccine, if only because it's difficult to say with strong confidence which approaches would definitely fail. Rather, it's a question of whether they actually did given the political dynamics. There's good reason to discount the credibility of claims coming from authoritarian regimes. (Reasons for which most Americans have a renewed appreciation, rightly or wrongly.)

I suspect it wouldn't be too difficult to fudge the numbers (e.g. candidate selection criteria) in such a way that a mediocre vaccine looks excellent. Until it's reproduced or until other opportunities for falsification arise, trusting a result is largely a matter of the personal credibility of the researchers and, importantly, the system in which they operate.