It’s not like this is some random event that could happen to any position. There seem to be a number of factors in play, but it’s not random, and it’s not because a meme got popular.

GP is not dismissing it. They're saying that a stock play turning into a meme is becoming a serious additional risk factor.

not at this price. There's a rationale for doing so at sub $10 a share.

Buy things, hold things, sell things.

A more-sophisticated investor than I could also hedge against undesirable long-tail events.

To me, with a long-term/value perspective, these transients are a bummer because they distract from efficient price discovery. But, with a long-term perspective, these transients are mostly irrelevant. If a quality company's price drops precipitously, it is then on sale and worth buying. If it becomes quickly inflated, I can either hold with a smile or, if it is just too insane, sell with the expectation of buying in again later. The only real risk is of a meme-driven fluctuation shorting an otherwise-okay company into bankruptcy.

Hide your position better. Put out fewer signals. Lobby to make trades secret.

Don't take short positions. They add nothing of value to anyone. They are just fancy gambling.