This is ahistorical. In many societies throughout history, an accusation of heresy was a mortal threat, or worse.
Today, there is no hiding - forever - even if you've atoned your mistakes.
From the wikipedia article on exile: "In Roman law, exsilium denoted both voluntary exile and banishment as a capital punishment alternative to death."
When something is an alternative to death, I think it's fair to say that it was not a trivial event. "Just" moving somewhere wasn't easy, historically.
It probably can, but unfortunately the people usually held up as examples of this generally haven't actually been ruined. I mean, what are some actual examples of people who have been ruined by accusation?
Social Media continues to perpetuate falsehoods about the case, trial and outcome. There is no safe place for Zimmerman in America today... and regardless of what you think of him as an individual, that's a problem.