It's worth noting that the most effectives breakthroughs against cancer in recent decades (Immunotherapy, angiogenesis-suppressing drugs) have largely been based on ideas that were first dismissed and widely ridiculed by senior scientists working on cancer research.

I suspect that in another 50 years, when the war against cancer is (finally) over, we will end up with a completely different perspective on the history of cancer research than the often self-serving and propagandized perspective we have today.

Just how radical were these ideas you speak of from the accepted dogma?

On angiogenesis, see Judah Folkman: https://www.tobinproject.org/about/judah-folkman

On cancer immunotherapy, see Fran Visco's story as partially told by Daniel Sarewitz (section titled "War on Cancer"): https://www.thenewatlantis.com/publications/saving-science

Thanks! They certainly like very illuminating insights. From my viewpoint epigenetics seems like the forerunner to many future revelations too.