Half-Life 2 was randomly crashing on AMD systems on launch. Valve was sometimes churning 4 updates/day. Then they requested some actual gamers with AMD systems to come to HQ for testing. After that point all bugs are ironed out in a week or so.

But blaming I/O bandwidth for bugs that are clearly related to game logic is naive.

Lazy loading assets with a slow I/O backbone might cause some glitches though. Unless you have a finicky storage controller, you can't create too much problem with a slow storage.

3700X / B550M / GTX 1660 here.

So far had one crash in looots of hours of play, which was a memory hog which ate my entire memory/allocatable region and then crashed the game (saw it slowly rise to 99% commit). Seems to be configuration dependant, who knows what setting causes it.