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Re:Vitamin D metabolites and the gut microbiome in older men by WalterSear on Thursday December 03, 2020 @01:42PM (#25292726)
Our most current understanding is that 7k iu is closest to optimal, and that previous recommendations were based on bad math.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541280/

While toxicity is a serious matter, the actual risk is generally overblown, since it requires truly heroic, sustained doses.

>The evidence is clear that vitamin D toxicity is one of the rarest medical conditions and is typically due to intentional or inadvertent intake of extremely high doses of vitamin D (usually in the range of 50,000-100,000 IU/d for months to years)

https://www.mayoclinicproceedings.org/article/S0025-6196(15)...

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