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Re:AlphaFold: a solution to a 50-year-old grand challenge in... by adw on Monday November 30, 2020 @11:34PM (#25262332)
> generative grammar/ symbolic approaches were pretty much left behind by NN methods

Which is the same thing as hand-engineered feature stacks being left behind in vision problems, really. The story in every field is more or less "you're not clever enough to engineer good features"; "you might be clever enough to define good symmetries for the feature space in which the features live... maybe" (convolutional neural networks in image problems); "... but maybe not even that" (attention mechanisms).

Re:AlphaFold: a solution to a 50-year-old grand challenge in... by snovv_crash on Tuesday December 01, 2020 @01:31PM (#25268172)
The hand generated features are still superior for SfM style problems, where the geometry is well defined but would need to be learned by the NN from scratch.