Re:No one who got Moderna's vaccine in trial developed sever...
by disgruntledphd2 on Monday November 30, 2020 @11:55AM
(#25255870)
Yeah, agreed.
My selfish concern is then whether or not the vaccine will work for them.
Re:No one who got Moderna's vaccine in trial developed sever...
by chimeracoder on Monday November 30, 2020 @12:13PM
(#25256129)
> My selfish concern is then whether or not the vaccine will work for them.
We won't have hard data on that specific question for a very long time, but it's something your/their doctor would be better equipped to make an educated guess about, given the specifics of their situation ("immunosuppressed" can mean a range of things). In some cases, a vaccine might do nothing. In some, it might be actively dangerous. In some, it might have a weaker but still nonzero protective effect. But I wouldn't trust anything you read on HN that tries tell you anything more specific than that.
Re:No one who got Moderna's vaccine in trial developed sever...
by tsimionescu on Monday November 30, 2020 @12:14PM
(#25256135)
Unfortunately, vaccines can't really help immunocompromised people, as their immune system is simply unable to fight off any infection, regardless of whether it recognizes the infection or not (of course, this may be a matter of degrees). That is why, for example, people with advanced AIDS can die from essentially any pathogen.
Re:No one who got Moderna's vaccine in trial developed sever...
by chimeracoder on Monday November 30, 2020 @12:17PM
(#25256186)
Your answer isn't exactly wrong, but it's painting with a broad brush. "immunocompromised" is a broad term (even more so than "immunosuppressed"), so there definitely are people who are immunocompromised who could potentially benefit from a vaccine (again, we don't have hard data on that yet for any of the vaccine candidates and won't for a while).
Re:No one who got Moderna's vaccine in trial developed sever...
by iso1210 on Monday November 30, 2020 @02:33PM
(#25257893)
They do help indirectly - by innoculating the 90% who can take a vaccine, the 10% who can't (for example babies when it comes to measles vaccines) are unlikely to actually catch the disease.
Re:No one who got Moderna's vaccine in trial developed sever...
by tsimionescu on Monday November 30, 2020 @03:55PM
(#25258850)
Oh, for sure, I wasn't trying to say vaccines shouldn't be used! They are extremely important to a healthy population overall, and it is all the more important for people with healthy immune systems to get them to help protect those that can't benefit directly.
There are other reasons a person would be considered immunosuppressed, and plenty of non-chemotherapy drugs that have immunosuppressive effects. But yes, cancer is one of them.
It would make no sense to include immunosuppressed people in the initial trials for a vaccine, the purpose of which is to determine whether a vaccine can induce an immune response.