I feel like this is the more important of the two points you made.
Even without Uranium, it's conceivable to have a second industrial revolution. We don't need nuclear power for that.
But without easily accessible fossil fuels, it's much harder to envision the next civilization having an industrial revolution. They might indeed never rise to our level of technology again.
knowledge is the key. Even Ancient Greeks could have built a wind electricity generator if they knew how - ie. if they knew about copper wire and electrical charge movement in it. And you can collect sun light and focus it on a boiler while still being in Ancient Greeks situation - that gives you https://en.wikipedia.org/wiki/Aeolipile which can be used to generate electricity too. And they could have possibly have that too https://en.wikipedia.org/wiki/Voltaic_pile or even https://en.wikipedia.org/wiki/Crystal_detector#Cat_whisker_d... - piece of crystal and a wire making a diode - and you can have primitive radio.
So, the newly built civilization bypassing fossil fuels would even be better :)
Did they have the level of materials science to build a practical one? They weren't able to produce steel, for example.
For some minerals (e.g. metals) that might possible even be a bonus, as we've brought it up to the surface and it might be more accessible than before (a scrapyard that's buried under some soil could be an excellent place to mine iron), but there won't be shallow coal or shallow oil that a second industrialization could use as a cheap power source.
We may be able to start low scale stuff to bootstrap renewables, but if we lose our knowledge, things get much harder.
For instance, so much of our early nuclear technology was dependent on the Shinkolobwe uranium mine in the DRC, and it's orders of magnitude better uranium purity than anything else we've found.
> Our best source, the Shinkolobwe mine, represented a freak occurrence in nature. It contained a tremendously rich lode of uranium pitchblende. Nothing like it has ever again been found. The ore already in the United States contained 65 percent U3O8, while the pitchblende aboveground in the Congo amounted to a thousand tons of 65 percent ore, and the waste piles of ore contained two thousand tons of 20 percent U3O8. To illustrate the uniqueness of Sengier's stockpile, after the war the MED and the AEC considered ore containing three-tenths of 1 percent as a good find. Without Sengier’s foresight in stockpiling ore in the United States and aboveground in Africa, we simply would not have had the amounts of uranium needed to justify building the large separation plants and the plutonium reactors [for the Manhattan Project].
~ Colonel Ken Nichols
Additionally, without the very dense energy in the easily accessible fossil fuels we've very nearly mined out, restarting an industrial revolution would be at best extremely problematic.
We've been OK so far with progress meaning we slam the door shut to independent replication of that progress in a lot of cases.