Certainly I believe that remote work was already on the way to becoming more and more accepted, but by moving out you're still limiting your employment prospects to those companies that decide not to focus more on in-person roles. Maybe that will still work out in the long-run, but I still think there's significant long-term financial benefit in maximizing your number of potential employers.

Plus, if you're expecting to move back to San Francisco at some point, right now is the time to do it while prices are through the floor. You're far better off moving in right now at a 35% discount—which is permanent given rent control—than trying to come back in another year when COVID-19 is (hopefully) over and people are flooding back in.