How Much Vitamin D Is Too Much? A Case Report and Review of the Literature

Re:How Much Vitamin D Is Too Much? A Case Report and Review ... by arkitaip on Friday October 09, 2020 @06:57PM (#24735261)

"The patient had been assuming very high dose of cholecalciferol since 20 months (cumulative 78,000,000UI, mean daily 130,000UI), as indicated by a non-conventional protocol for multiple sclerosis."

"This case confirms that vitamin D intoxication is possible albeit with a really high dose."

This is a truly insane dosage but all this case says is that however created this protocol is dangerously incompetent.

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Re:How Much Vitamin D Is Too Much? A Case Report and Review ... by hinkley on Friday October 09, 2020 @08:06PM (#24735648)

I guarantee if you get MS you’ll do some pretty crazy shit too, probably crazier than this.

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Re:How Much Vitamin D Is Too Much? A Case Report and Review ... by reco on Friday October 09, 2020 @09:27PM (#24736023)

What are you talking about? I have several family members with MS and they don’t do stupid shit they learned off YouTube.

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Re:How Much Vitamin D Is Too Much? A Case Report and Review ... by pmiller2 on Friday October 09, 2020 @06:59PM (#24735275)

Yeah, 130K IU / day is ~20x what's typically regarded as safe.

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Re:How Much Vitamin D Is Too Much? A Case Report and Review ... by radu_floricica on Saturday October 10, 2020 @01:49AM (#24736923)

There's safe and safe. 20x the safe dose of cannabis will make you very stoned for a while, 20x the safe dose for alcohol will kill you. Similarly an overdose of vitamin D vs aspirin.

The relevant metric here is LD50 - but a quick google doesn't find a number for vitamin D. A wild guess would be that the patient in question could have died, though whether the odds were 50% we can't really say from just one case. But it means that 130000 UI daily for over a year is in the ballpark.

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Re:How Much Vitamin D Is Too Much? A Case Report and Review ... by LegitShady on Friday October 09, 2020 @08:01PM (#24735632)

taking 20x the recommended dose of water (3-4 liters daily - 60-80 liters to compare) will kill you too.

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Re:How Much Vitamin D Is Too Much? A Case Report and Review ... by userbinator on Friday October 09, 2020 @09:33PM (#24736064)

...and people have died from it: https://en.wikipedia.org/wiki/Water_intoxication

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Re:How Much Vitamin D Is Too Much? A Case Report and Review ... by Florin_Andrei on Friday October 09, 2020 @09:22PM (#24735996)

> protocol

I wonder if that's an euphemism for "stuff they learned on youtube".

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