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Re:'Long Covid': Why are some people not recovering? by fab1an on Tuesday October 06, 2020 @10:15AM (#24697831)
Good to see some data on how common/uncommon this may be: it seems that 2% of confirmed patients suffer from some form of "Long Covid", which definitely isn't great news, but certainly better than what some overeager media have irresponsibly reported (the Rome study comes to mind, where hospitalized patients where somehow taken to be representative of the entire pool of infected people).

One does wonder about the 'nocebo' factor, too - if you've been told to watch out for lingering symptoms are an infection that certainly affects the way in which you are observing your own body, especially so if you're even minimally hypochondriac. There is an understandable media narrative to portray mostly severe cases (again, understandable from some sort of public health perspective) but that also adds to psychological add-on effects one might face with this disease.

I'm in no way part of the just-the-flu crew, but feel that the OMG-COVID crew hasn't necessarily thought the above aspects through either.

Re:'Long Covid': Why are some people not recovering? by cheph on Tuesday October 06, 2020 @10:28AM (#24697981)
> I'm in no way part of the just-the-flu crew, but feel that the OMG-COVID crew hasn't necessarily thought the above aspects through either.

The incentives are all messed up for the media to provide a balanced information and with the economic devastation coming down the pipes I think both the flu and COVID will look like a walk in the park.

https://blogs.worldbank.org/developmenttalk/lives-or-livelih...

> Using those somewhat more generous – but still frugal – thresholds, the number of poverty years in the world (235 million) is 54 times the number of lost years.

And yes, without lockdowns things may be even worse, but the fact remains that the biggest impact on lives from this pandemic will likely not be directly from COVID but indirectly from economic devastation.

Re:'Long Covid': Why are some people not recovering? by matwood on Tuesday October 06, 2020 @10:33AM (#24698048)
> And yes, without lockdowns things may be even worse, but the fact remains that the biggest impact on lives from this pandemic will likely not be directly from COVID but indirectly from economic devastation.

You say indirectly, I say directly. Even if everything was opened 100% tomorrow, many people are simply not going to go back to what they used to do. The way to avoid economic devastation was/is to deal with covid.

Re:'Long Covid': Why are some people not recovering? by djsumdog on Tuesday October 06, 2020 @10:42AM (#24698132)
Things are pretty much back to normal in parts of Mississippi:

https://neckbeard.xyz/notice/9znbtKqgRaGgwdVxgm

..and the secondary effects of the economic and psychological devastation are pretty bad. I wrote this back in July:

https://battlepenguin.com/politics/secondary-effects/

It's been eight months! We cannot keep living like this. We know now the largest deaths came from a failure to protect the elderly and misusing nursing home facilities (Michigan, Kirkland/Seattle, NYC). We need to do more to protect the elderly, but other people need be able to assume their own risks again.

Most lockdown restrictions have ended in Ecuador. Florida and Mississippi are opening up. Pennsylvanian had a cord order by Stickman to open up, but it's been stayed pending appeal.

Humanity cannot be put into low power mode like a laptop. We are not cogs in a machine that can be stopped and started at will.

Re:'Long Covid': Why are some people not recovering? by NationalPark on Tuesday October 06, 2020 @11:17AM (#24698576)
Daily new cases in Mississippi are still pretty bad. Removing restrictions because you feel like you should be done with the virus is just going to drag this out.
Re:'Long Covid': Why are some people not recovering? by djsumdog on Tuesday October 06, 2020 @05:15PM (#24702409)
and yet Sweeden is doing very well. What is your long term goal/solution exactly? This thing isn't going away. Keeping people locked up delays infections, it doesn't stop it.
Re:'Long Covid': Why are some people not recovering? by rweir on Wednesday October 07, 2020 @10:53AM (#24708872)
the US hasn't even been able to match the measures[0] Sweden put in place, though? there's still thousands of people showing up with no masks to breath on each other at rallies etc

[0]: https://www.newscientist.com/article/2251615-is-swedens-coro...

Re:'Long Covid': Why are some people not recovering? by matwood on Wednesday October 07, 2020 @08:50PM (#24714538)
Sweden’s voluntary measures were/are likely followed better than the patchwork of measures in the US. I’m not sure they can be used as an example of anything that’s possible in the US.

Also, this whole ‘locked up’ straw man is growing tiresome. There is a large gradient between locked up and going out like there is no pandemic.

Re:'Long Covid': Why are some people not recovering? by gotoeleven on Tuesday October 06, 2020 @10:57AM (#24698317)
It's getting to the point on HN where the informative posts are greyed out and you have to find them before they get killed completely. Sad!
Re:'Long Covid': Why are some people not recovering? by sharken on Tuesday October 06, 2020 @11:25AM (#24698690)
I agree that dealing with Covid is the way to go forward, but we simply cannot drag our feet with restrictions until summer/fall of 2021.

If politicians choose to do so anyway, they should know that economic devastation can be a very real outcome from going down that path.

Re:'Long Covid': Why are some people not recovering? by matwood on Tuesday October 06, 2020 @11:51AM (#24699040)
Define restrictions. There is a large area between lockdown and doing nothing. Anytime I see people arguing about 'restrictions', it's usually a straw man of going back to a total lockdown. No one is talking about doing that nationally, and even locally it would only be in extreme cases of uncontrolled community spread.

If we hadn't politicized the virus every step of the way, we could have adopted some simple mitigation measures that would have already gotten us back to some level of normal. A national strategy of masks and distance could have kept things mostly open/got things re-opened. If people were generally trying to limit the spread, testing and contact tracing would work to control outbreaks.

Instead the US has a patchwork of rules with uncertain national leadership hoping the virus just disappears. All we have done is extend the time we have to deal with this mess, and possibly cause more deaths than necessary.

And, I just saw that the POTUS once again tweets it's just like the flu (which doesn't kill 100k Americans/year), further downplaying and extending how long any COVID recovery will take.

Ultimately, the 'economic devastation' you mention is not from the lockdowns, but our complete ineptitude around dealing with pandemic.

Re:'Long Covid': Why are some people not recovering? by gizmo on Tuesday October 06, 2020 @10:33AM (#24698041)
So many people have been infected by covid in the last 9 months that you'd expect a large enough number of infections to coincide with other health problems to make for scary headlines. If somebody has a something as mundane as burnout or depression after catching covid, will people identify it correctly, or will anxiety and relentless doom and gloom news headlines result in a "long covid" self-diagnosis?

Do we have any reason to believe long covid is a real thing? Is this not just anecdotes being blown up by the media that is generally useless at science reporting?

Re:'Long Covid': Why are some people not recovering? by JimmyAxod on Tuesday October 06, 2020 @10:51AM (#24698239)
I got covid in March, I’ve had “long covid” since, or post virus fatigue...

It’s certainly a real thing :)

There’s many symptoms, but as most articles state, the main one being extreme fatigue, second one is probably brain fog. Another is breathing issues.

When it gets bad for me, I make extreme noises every so often when I sit down, or when I need to take a big breath of air, etc etc Eating can be exhausting - both because you’re spending energy chewing etc, but also you’re not able to breathe as much...

I agree with you, that since it coincided with lockdown, people out of jobs, not being active etc, then it could sometimes be misdiagnosed, but it’s very different and pretty easily spotted.

Re:'Long Covid': Why are some people not recovering? by oceanplexian on Tuesday October 06, 2020 @11:10AM (#24698462)
I got the same symptoms of "long covid" and didn't even contract the virus. The lockdowns making it illegal to go to a bar or a sports game, worrying about finances and the economy, the incessant negative politics and media, wearing masks all day, replacing real human contact with computer screens and "Zoom Happy Hours"? All of these have given me the same symptoms: Anxiety. Fatigue. Brain Fog. Breathing issues. It seems like there is another disease going around and no one is talking about it.
Re:'Long Covid': Why are some people not recovering? by gnusty_gnurc on Tuesday October 06, 2020 @12:22PM (#24699450)
> All of these have given me the same symptoms: Anxiety. Fatigue. Brain Fog. Breathing issues. It seems like there is another disease going around and no one is talking about it.

It feels great to see someone else with a similar experience.

As someone with a history of anxiety with somatic symptoms, I deal with this stuff, even digestive weirdness. How many times over the course of the pandemic have I felt like I can't breath?

I'm keenly aware of my mental health and how it affects me. I know that there are certain states of mind/dispositions that I need to assume in order to feel stable.

In normal times, I go about life and forget about my anxiety because my daily routine is a good distraction.

Maybe this isn't obvious to people without anxiety, but it's clear to me that way too many people are inhabiting unhealthy relationships with danger, fear, anxiety, etc.

And it's sad cause it seems like politics and technology is trapping people in that mindset.

I'm frankly sick and tired of the people condemning others as though it's immoral to not be afraid of COVID. You can understand COVID is potentially dangerous while not really worrying about it.

This is an essential technique for people with anxiety if they ever want to lead a normal and healthy life, but the zeitgeist is full on fire-and-brimestone moral righteousness and preaching if you're not absolutely consumed with fear and anxiety over a virus that almost all people survive.

I don't want to say "long COVID" isn't real especially since there so little understanding about any of this, but I would say it's more likely than not that many people are predisposed to somatic symptoms of anxiety, power of suggestion, etc. especially when large segments of the population are trapped inside for long periods of time and deprived of social activity.

Re:'Long Covid': Why are some people not recovering? by milesvp on Tuesday October 06, 2020 @12:05PM (#24699210)
You are right that a lot of the symptoms can be attributed to other health issues around lockdown. I will say though, that I personally experienced a long period of weird fatigue just prior to lockdown. I’d had weird not quite flu symptoms that didn’t quite fit the covid symptom list at the time. But due to timing of dinner with someone who later tested positive for covid, I have reason to think I may have actually had covid.

The fatigue was really stange, like pushing my kids on the swing made me pause for strength. And chasing my kids for more than a few steps made me wheeze and gasp for breath.

The fatigue lasted at least a month. And was definitely different than the effects of anxiety that happened later. Especially since exercise tends to be invigorating for me in the face of anxiety.

This isn’t to say that there aren’t also lockdown related health problems conflating the issue, but I have personal reasons to think long covid is a thing, especially when looking at all the system the virus seems to ravage.

Re:'Long Covid': Why are some people not recovering? by adaml_623 on Tuesday October 06, 2020 @12:54PM (#24699914)
I agree with you that there is another disease going around but lots of people are talking about it.

I can't tell if you're making a joke but anxiety has all those symptoms and it's obviously increasing and people are talking about it.

Re:'Long Covid': Why are some people not recovering? by JimmyAxod on Tuesday October 06, 2020 @04:02PM (#24701759)
I haven’t got anxiety at all. It’s very very different.
Re:'Long Covid': Why are some people not recovering? by gizmo on Tuesday October 06, 2020 @12:32PM (#24699606)
Did you have a bad case of covid? Any serious lung infection can result in the symptoms you describe. No shortage of people who report similar for two years after flu induced pneumonia. But with the flu it's people who get seriously ill who need a long time to recover. With covid the extraordinary claim is that a significant percentage of people who catch it but are mildly symptomatic throughout still experience major loss of lung function, fatigue, etc. I find it hard to believe that perfectly healthy people get a debilitating "long covid" illness after a very mild covid infection.
Re:'Long Covid': Why are some people not recovering? by SpicyLemonZest on Tuesday October 06, 2020 @11:00AM (#24698353)
I think there are two separate things being conflated into the term "long Covid".

Do we have reason to believe that lingering fatigue, cough, etc. is a real thing? We do. Any serious infection can cause these things, and (as quoted in the article) some experts in the area say they're more common and severe than would normally be expected.

Do we have reason to believe that Covid causes some crippling disability that can never be treated or recovered from? Not strong ones, although of course even weak and inconclusive evidence should be investigated with a novel disease.

Re:'Long Covid': Why are some people not recovering? by michaelbrave on Tuesday October 06, 2020 @12:25PM (#24699519)
I don't know if I would call it a crippling disability, but there are likely some permanent bloodclot related problems afterward for many.
Re:'Long Covid': Why are some people not recovering? by oceanplexian on Tuesday October 06, 2020 @11:03AM (#24698384)
> I'm in no way part of the just-the-flu crew

One thing I don't get is why saying C19 is "Just another Flu" is somehow taken as downplaying the virus. Seasonal Flu kills as many as 600,000 people annually. Do their lives not matter because they are taken by a regular old virus and not a novel coronavirus? And why doesn't the media report on every strain and mutation of the seasonal flu that could cause "long term effects"?

Re:'Long Covid': Why are some people not recovering? by nickfromseattle on Tuesday October 06, 2020 @11:22AM (#24698645)
COVID19 has caused 250,000+ additional deaths in the US on-top of whatever the normal flu kills in an average year.

Here is a link for more information on 'excess death': https://ourworldindata.org/excess-mortality-covid

Re:'Long Covid': Why are some people not recovering? by funcDropShadow on Tuesday October 06, 2020 @11:30AM (#24698772)
The seasonal flu is a severe disease. Let's say it kills 600,000 people on average per year. That is not measured like the Covid death are measured in most countries. For the flu they take the excess death to estimate how many people died. But the majority of people are not tested. Whereas we are doing extremely hard counter measures against Covid-19, and we still have more deaths than for the seasonal flu. And the flu and Covid-19 season is just starting in the northern hemisphere. On top of that we have the long Covid phenomenon. But is's incidence is still unclear. But even if it is just 2% of Covid cases, that are ill for month (if not for years), that is really quite significant; even expensive for the economy.

So, I don't see Covid-19 as "just like the flu".

Re:'Long Covid': Why are some people not recovering? by foogazi on Tuesday October 06, 2020 @01:49PM (#24700485)
We don’t lock down for Seasonal Flu and there is an annual vaccine for it with regular reminders to get your flu shot

Covid-19 has been around for less than a year, no vaccine and, with a lockdown and closing our borders, has already killed 3x more than the seasonal flu in the US

So it’s not like the flu

Re:'Long Covid': Why are some people not recovering? by conception on Tuesday October 06, 2020 @11:26AM (#24698692)
Because Covid is about a magnitude more deadly. And seems to have more long term effects than the flu typically does.

It’s not just another flu. Saying it is is downplaying it.

Re:'Long Covid': Why are some people not recovering? by rattray on Tuesday October 06, 2020 @10:46AM (#24698186)
Hmm, that's a bit of a rosy interpretation – the article also says this:

> Half of people in a study in Dublin still had fatigue 10 weeks after being infected with coronavirus. A third were physically unable to return to work.

> Crucially, doctors found no link between the severity of the infection and fatigue.

Study here: https://www.medrxiv.org/content/10.1101/2020.07.29.20164293v... 128 participants (49.5 ± 15 years; 54% female)

Re:'Long Covid': Why are some people not recovering? by arcticbull on Tuesday October 06, 2020 @11:15AM (#24698544)
“fatigue” is one those symptoms that’s heavily affected by placebo/nocebo since it’s predominantly psychological. I’m not saying it can't be caused by a lingering infection or the result of an infection, I’m just saying it’s not like “scarring” or “breathlessness” — it’s hugely subjective. IMO the fact there’s no correlation to disease severity points more towards this being a red herring.

[edit] To downvoters, consider that the placebo effect is incredibly strong, much stronger than you give it credit for most likely, and has gotten stronger over time as our faith in medicine has.

A 2014 study showed that placebo was 50% as effective as real migraine medication in treating pain after migraines [1].

Similarly for the nocebo effect. A study showed that 20% of people getting placebo drugs in a clinical trial developed side-effects. The nocebo effect may be even stronger than placebo. [2,3].

I'm not minimizing COVID and I'm not saying these people are "making it up." I'm saying, humans aren't computers, and human viruses aren't computer viruses. It's not a case of X happens to you and the result is deterministically Y. There's a lot more to your subjective experience. Generally the more strongly you believe in a potential range of outcomes, the more likely you are to, basically, get them. COVID anxiety is huge, and some of these "long-haulers" symptoms could easily be nocebo.

If this long-haul syndrome really is nocebo, it opens up potential avenues for treatment.

We need to keep an open mind.

[1] https://www.health.harvard.edu/mental-health/the-power-of-th...

[2] https://www.health.harvard.edu/newsletter_article/The_nocebo...

[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804316/

Re:'Long Covid': Why are some people not recovering? by adaml_623 on Tuesday October 06, 2020 @12:28PM (#24699558)
Your statement about the lack of correlation of disease severity and fatigue made me think of a few question.

* What is the measure of disease severity?

* Is there a correlation between measures of disease severity and anosmia in Covid-19?

* Is there a correlation between disease severity of other viruses that trigger chronic fatigue symptoms and incidences of CFS?

The anosmia question seems relevant if we assume that the virus damages the nervous system.

Re:'Long Covid': Why are some people not recovering? by tremon on Tuesday October 06, 2020 @02:17PM (#24700731)
“fatigue” is one those symptoms that’s heavily affected by placebo/nocebo since it’s predominantly psychological.

Be very careful with how you phrase that. Fatigue is very much a physical thing, not psychological. It's just that medically, we have no way to quantify it, so it doesn't show up easily in lab tests. That does NOT mean it doesn't exist, or that it only exists in the head. (edit: and before someone says "lactate", keep in mind that that only measures muscle strain, one of the few forms of fatigue that we do know how to measure)

How people experience fatigue has a psychological component, but saying to someone who has been fatigued for years that their issues are predominantly psychological is very dismissive. Odds are they've been hearing that from their physicians for a long time already.

Re:'Long Covid': Why are some people not recovering? by sharken on Tuesday October 06, 2020 @11:16AM (#24698562)
Not a study but the COVID Symptom Tracker App has registered one in 200 with side-effects 90 days later.

Source: https://news.sky.com/story/coronavirus-more-than-half-of-cov...

So anywhere from 0.5% up to 2% seems to be the plausible range, which of course can differ depending on your age.

Re:'Long Covid': Why are some people not recovering? by rattray on Tuesday October 06, 2020 @01:13PM (#24700113)
The source you cite has the following headline: "More than half of COVID-19 patients experience ongoing fatigue, study finds"

So I'm not sure why that article gives you the impression that any more than 2% is implausible.

When I see a medical journal article with n~150 saying that 50% experience fatigue after ~70 days, and an app reports that self-reported "symptoms" (may not be asking about fatigue?) are below 2% after 90 days, my takeaway is that much more data is needed because it could be that "a lot of people have long-lasting side-effects".

Think about if you (or a young healthy family member) tested positive and felt mostly fine for a week or two.

After reading both of the above, I'd be concerned that there's a decent chance (1%-60%?) that you'd be worse off in some way for a long time, possibly the rest of your life.

Re:'Long Covid': Why are some people not recovering? by LeoNatan25 on Tuesday October 06, 2020 @10:20AM (#24697895)
2% is actually a very large percent, considering how contagious the virus is. Many people like to say that all respiratory illnesses produce similar issues, but no other so widespread virus has such high chronic illness remains.
Re:'Long Covid': Why are some people not recovering? by agent008t on Tuesday October 06, 2020 @10:23AM (#24697932)
The symptoms sound similar to the longer-term effects some people experience with mono (Epstein-Barr virus / glandular fever).
Re:'Long Covid': Why are some people not recovering? by JimmyAxod on Tuesday October 06, 2020 @10:35AM (#24698068)
I’ve had both. This (long covid, post virus fatigue, whatever) is a few orders of magnitude worse, at least for me.

I had covid middle of March, and am maybe 50% energy most days, and have to do massive breaths every so often. After 7 months of “recovery”?! I don’t know if I’m even getting better... yeah extreme fatigue, brain fog, eating can be exhausting...

OTOH, A lot of people came out of it far worse...

Re:'Long Covid': Why are some people not recovering? by agent008t on Tuesday October 06, 2020 @01:38PM (#24700386)
Looking up "mono brain fog", there seem to be a lot of reports of people experiencing neurological symptoms for many months, even years. Symptoms reported are similar - fatigue, brain fog, decreased appetite, some also seem to report anxiety and other similar changes.

But it seems to be rare enough that it is hard to establish a causal link / study it properly.

I wonder if there could be some common cause? Perhaps also common to CFS?

Re:'Long Covid': Why are some people not recovering? by abathur on Tuesday October 06, 2020 @12:06PM (#24699230)
Thanks for this comparison.

I'm not sure how common symptomatic mono is, but I suspect it (along with some things like maybe pneumonia and bronchitis?) is a good reference point.

How was your bout with mono? I recall having tonsils so swollen I was afraid I'd have to go to the hospital for a few days, and then being perpetually exhausted for ~6-8 weeks.

Re:'Long Covid': Why are some people not recovering? by JimmyAxod on Tuesday October 06, 2020 @04:04PM (#24701772)
Yeah for me mono was horrible for a week or so, then exhaustion for 2-3 months but nothing like long covid. Of course it could also be partly the fact I had mono in my early 20s and had covid in early 40s!
Re:'Long Covid': Why are some people not recovering? by lucideer on Tuesday October 06, 2020 @10:42AM (#24698133)
The 2% figure is from an app that has been plagued with technical issues[0] since its release.

The article also highlights a study[1] finding over 50% suffered fatigue after 10 weeks and 33% were physically unfit to work. From that study:

> There was no association between COVID-19 severity (need for inpatient admission, supplemental oxygen or critical care) and fatigue following COVID-19

[0] https://www.reuters.com/article/uk-health-coronavirus-britai...

[1] https://www.medrxiv.org/content/10.1101/2020.07.29.20164293v...

Re:'Long Covid': Why are some people not recovering? by SpicyLemonZest on Tuesday October 06, 2020 @11:05AM (#24698394)
This study's sample was pretty strongly non-representative; half the subjects had been hospitalized.
Re:'Long Covid': Why are some people not recovering? by ourcat on Tuesday October 06, 2020 @10:27AM (#24697976)
I know a couple of people who caught Covid-19 back before the summer, who both described the same symptoms after recovering (and testing negative). This was a while before all this talk of 'Long Covid' came about.

Since we're all different, and will all fight viruses in different ways and strengths (depending on health/existing cnditions etc.), there'll be so many variations in how much of a 'toll' fighting it has taken on our bodies (and minds).

Since this ia a 'novel' virus, we can only really base any conlusions on the empirical evidence as it comes in.

Re:'Long Covid': Why are some people not recovering? by oceanplexian on Tuesday October 06, 2020 @10:53AM (#24698260)
The virus shouldn't have been labeled 'novel' in the first place. In a 2020 study by La Jolla Institute for Immunology, they found blood samples pre-2018 that demonstrated a T-Cell immune response to Covid-19. It was found that in SARS-CoV-2 and “common cold” coronavirus fragments that were similar (at least 67% genetic similarity) 57% showed cross-reactivity by memory T cells. If the Covid-19 coronavirus is novel, then we should be designating every new strain of the flu as a novel virus.
Re:'Long Covid': Why are some people not recovering? by SomeoneFromCA on Tuesday October 06, 2020 @03:47PM (#24701608)
This is a very weird distortion of terminology. I get it, you hate anti-covid measures (I read your other posts), but most of the "common old" coronaviruses are wildly different from the SARS-2 virus, 67% of genetic difference represent hundreds of years of evolution; the only "similarity" they have is belonging to the same family of coronaviruses. It is like saying, yeah we share 99% of genes with monkeys therefore we are the same thing.
Re:'Long Covid': Why are some people not recovering? by juliushuijnk on Tuesday October 06, 2020 @11:09AM (#24698452)
If you have many hours to spare, you can watch George Hotz dive into the details. One of the take-aways is that the Corona virus is a Sars, not a flu.

https://www.youtube.com/watch?v=8vWaawiUteM

If your take is that Sars is just another flu, then I guess you just broadened the scope of the flu, and need to be open for the idea that the 'flu' could be more dangerous than you thought.

Re:'Long Covid': Why are some people not recovering? by notahacker on Tuesday October 06, 2020 @11:11AM (#24698487)
Fragments that were 67% similar really doesn't sound very similar when we're talking about DNA, considering us slower evolving mammals share a larger percentage of DNA with our pets, and by your own stat 43% of people's T-cells are not primed to respond at all...

We do designate strains of influenza transmitted from animals (and indeed other coronaviruses transmitted from animals) as novel threats.

Re:'Long Covid': Why are some people not recovering? by oceanplexian on Tuesday October 06, 2020 @11:22AM (#24698642)
The human genome contains 3 billion nucleotides, SARS-COV-2 contains about 29,000. If it shares ~60% of its genome with common coronaviruses that's quite substantial.
Re:'Long Covid': Why are some people not recovering? by djsumdog on Tuesday October 06, 2020 @10:35AM (#24698072)
> The mean age was 56.5[0]

There are potential long term effects from most infections, especially in the elderly. Other infections can cause long term problems, and it's still super early for COVID to talk about long term effects. I remember getting pneumonia in my twenties and it taking 3 months for my lungs to fully recover.

We still don't understand exactly what happens with Lymes Disease. Is the immune system left in a state where it's continually fighting/reacting to an infection that's no longer present?

The 1976 swine flu vaccine also may have cause neurological issues for up to 4,000 of the millions who received it[1]. Would they have had the same symptoms from an actual infection from the flu? Potentially. It'd difficult to know, but people do have long term issues from other viruses, especially if they're older or have other underlying health conditions. It's not unprecedented.

[0]: https://jamanetwork.com/journals/jama/fullarticle/2768351

[1]: https://www.youtube.com/watch?v=4bOHYZhL0WQ (60 Minutes)

Re:'Long Covid': Why are some people not recovering? by kalaido on Tuesday October 06, 2020 @10:48AM (#24698212)
I agree. It's like a maginfing glass