Re:Americans are getting more nervous about what they say in...
by ColanR on Wednesday July 29, 2020 @11:30AM
(#23987733)
The specific circumstances where the drugs are effective aren't being met. I didn't look up the details before.
https://academic.oup.com/aje/article/doi/10.1093/aje/kwaa093....
> Evidence about use of hydroxychloroquine alone, or of hydroxychloroquine+azithromycin in inpatients, is irrelevant concerning efficacy of the pair in early high-risk outpatient disease. Five studies, including two controlled clinical trials, have demonstrated significant major outpatient treatment efficacy.
Re:Americans are getting more nervous about what they say in...
by irishjohnnie on Wednesday July 29, 2020 @12:13PM
(#23988412)
ICYMI lots of issues with that study, https://academic.oup.com/aje/article/doi/10.1093/aje/kwaa155... https://academic.oup.com/aje/article/doi/10.1093/aje/kwaa156...
Re:Americans are getting more nervous about what they say in...
by ColanR on Wednesday July 29, 2020 @05:55PM
(#23992004)
I'm really sorry, I linked the wrong article. The quote in my comment is from the abstract of this [1] study. It's a meta-analysis by a professor of epidemiology at Yale. He also wrote an op-ed that ran in Newsweek. [2]
[1] https://academic.oup.com/aje/article/doi/10.1093/aje/kwaa093...
[2] https://www.newsweek.com/key-defeating-covid-19-already-exis...
Wrong. See, e.g., https://medcitynews.com/2020/07/hydroxychloroquine-flunks-ph...
“Results of the randomized, controlled, open-label Phase III trial, which took place at more than two dozen sites in Brazil, were published in the New England Journal of Medicine on Thursday. The study randomized 667 patients to receive hydroxychloroquine or the drug plus the antibiotic azithromycin on top of standard of care or standard of care alone. When patients were measured on the seven-point ordinal scale of improvement in disease, those in the two hydroxychloroquine groups showed no improvement compared with patients who received standard of care alone. Moreover, those receiving hydroxychloroquine more frequently experienced Qt prolongation and elevation of liver enzymes.”