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Re:Breach exposed more than one million DNA profiles on a ma... by anderspitman on Wednesday July 22, 2020 @08:35PM (#23923041)
Nebula is definitely an interesting entry into the market. There's also Dante Labs[0], which often offers 30x whole genome in the 200-300USD range. You can download all your raw data (including FASTQs, h37-aligned BAMs, and VCFs) from AWS. There are some quality concerns (and they use BGI instead of Illumina sequencers), but at that price it's tempting to do Dante and Nebula as a check on each other.

Dante also has what seems like a pretty good privacy policy, including an option to destroy your saliva sample and delete all your data[1]. Obviously you still have to trust them, but it's a step in the right direction.

There's a good Facebook group for customers of both Dante and Nebula[2].

[0]: https://www.dantelabs.com/

[1]: https://us.dantelabs.com/pages/privacy-policy

[2]: https://www.facebook.com/groups/373644229897409/

Re:Breach exposed more than one million DNA profiles on a ma... by kbenson on Wednesday July 22, 2020 @09:10PM (#23923223)
> including an option to destroy your saliva sample

Until I read that sentence, it honestly never occurred to me they would keep that around. The data, sure. Biological samples? I just assumed they would be disposed of after use.

Re:Breach exposed more than one million DNA profiles on a ma... by Figs on Wednesday July 22, 2020 @09:20PM (#23923280)
Ever heard of HeLa cells?

https://en.wikipedia.org/wiki/HeLa

Re:Breach exposed more than one million DNA profiles on a ma... by jcims on Wednesday July 22, 2020 @11:13PM (#23923837)
RadioLab did a great episode on Henrietta's story

https://www.wnycstudios.org/podcasts/radiolab/segments/91716...

Re:Breach exposed more than one million DNA profiles on a ma... by andrewem on Thursday July 23, 2020 @12:31AM (#23924194)
A sample can be used for multiple analyses. For instance, a customer might pay for autosomal DNA analysis and later want to pay extra for mitochondrial DNA analysis. If the sample has been destroyed, no problem just send in a new sample - unless the subject has died in the meantime.
Re:Breach exposed more than one million DNA profiles on a ma... by FreeTrade on Wednesday July 22, 2020 @09:16PM (#23923260)
Collect it all.
Re:Breach exposed more than one million DNA profiles on a ma... by philsnow on Wednesday July 22, 2020 @10:53PM (#23923736)
No reason to discard it, better sequencers are always around the corner
Re:Breach exposed more than one million DNA profiles on a ma... by bredren on Wednesday July 22, 2020 @09:22PM (#23923290)
Is it strange to suggest discussing anything on Facebook, given how little privacy is afforded to users?

I find it just a bit weird that products that customers recognize require privacy as a core tenant would also just head on over to Facebook to add new, targeted meta to their verified Facebook profile.

Re:Breach exposed more than one million DNA profiles on a ma... by chrisweekly on Wednesday July 22, 2020 @10:28PM (#23923604)
agreed w your observation; yes it's strange / weird, almost unfathomable.

also, in a genuinely non-pedantic, "aiming to help and educate, not nitpick" way, may I offer this tidbit:

tenant: legal inhabitant / renter / occupant

tenet: principle or belief