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Re:Genes, blood type tied to risk of severe Covid-19 by zosima on Thursday June 18, 2020 @03:30PM (#23566822)
The reason for the low cutoff is to correct for multiple hypothesis testing.

Any what do you mean by "opposite of how p-values work"?

Obviously if P(data or more extreme|null hypothesis) = 10^-8 it's significantly less likely to see the data if the null hypothesis was true, than if P(data or more extreme| null hypothesis) = 10^-7.

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