The only problem is I don't remember Flash or FF crashing before, except some rare occasion. Now I see Flash crashes somewhat often.
In every tab, all flash elements become gray. I'd rather just one tab crash that parts of many tabs crashing.
Note: Firefox used to crash the entire browser when Flash crashed so the method that Chrome and Firefox now use is an improvement.
I enjoy the speed and simplicity of chrome. For development work, I actually prefer the webkit DOM inspector to firebug. I was never a heavy plugin user to begin with, so firefox never tempted me much there. I think that if you're not planning on using plugins, the core browser features of chrome are more polished (again, this is just my opinion). If you're a heavy plugin user though, ff or opera is the way to go.
Firefox is quite the opposite.
The difference was enough for me to forgo the whole list of extensions that I used in Firefox (this was before Chrome even had extensions)
I switched about a couple of years ago - maybe things have improved since.
At work I can only use Firefox or IE so no brainer there - I use Firefox. At home I use Firefox but generally have Chrome open to play the odd Facebook game. The thing that puzzles me is I really don't notice any difference in performance between Chrome and Firefox and never have. I have a 4mb internet connection at the moment but noticed nothing different when I had 8.
The only reason I use Chrome is to play around with any HTML5 stuff and simple curiosity. With Firefox's huge add on libraries, Firebug, Tab controls etc I honestly cannot see why so much fuss is made about Chrome!