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Re:SQLite as an Application File Format (2014) by pilif on Saturday June 13, 2020 @11:51AM (#23510268)
SQLite has encryption plugin support, or you could encrypt the file yourself at rest. However, no matter what you are doing, as the application needs to be able to decrypt the file, you have to ship the key and thus the protection will be able to be circumvented.

It’s really not worth the effort IMHO

Re:SQLite as an Application File Format (2014) by bstar77 on Saturday June 13, 2020 @11:55AM (#23510305)
That's a good point... I don't want to have the game rely on "phoning home" to decrypt the db.
Re:SQLite as an Application File Format (2014) by yellowapple on Saturday June 13, 2020 @08:00PM (#23513934)
On top of that, even if you did have the game "phone home", that doesn't do much against someone inspecting the memory of a running game; one could just wait until the game does have the decryption key.