I recommend NOT implementing plugins in JavaScript with the Ducktape JS layer. I strongly recommend writing plugins in Lua for maximal compatibility and performance.
Why's that? We wrote it to be functionally identical to the Lua plugin (the code base is the same), so engine and language apart they should behave pretty much the same way. Is there any known issue or limitation you're aware of?
We have made some modifications to the Janus video room plugin but only to fix bugs or provide specific functionality we needed for certain gaming use-cases. Out of the box, the plugin is already very featureful. The key is to always stay up to date with master, the project is fairly active and so keeping up to date is very important.
We have debated writing our own plugin and that's certainly a possibility in the future. (There is a Duktape JS layer available) To be completely transparent, if we were to reach that need, I would re-evaluate the solution with more recent alternatives, like pion.ly.